edge research has revealed some of the key vicious cycles of negative
knock on effects that we see in Chronic Fatigue (CFS) and Fibromyalgia
These same vicious cycles
ultimately result in the baffling array of symptoms that patients
present which in turn makes treatment so complicated, difficult and
frustrating for sufferers, their doctors and complementary therapists.
But with every passing month we
are getting ever closer to
understanding the core system insults and failures, and with this
improved knowledge comes superior treatment strategies and advanced
protocols based on addressing real organic changes in the body.
This latest research is particularly welcome and aligns itself with the
vicious downward cycle of Chronic Fatigue and Fibromyalgia theories.
In so many CFS and Fibromyalgia patients digestive, gut and intestinal
problems are a mainstay of the symptoms presented.
Many patients declare some form of digestive, intestinal or bowel
dysfunction pre or post onset of the recognized trigger for their
In the early stages of CFS and Fibromyalgia illnesses many patients
will have taken broad spectrum antibiotic regimes aimed at wholesale
elimination of dangerous or bad bacteria from the gut. Lymes disease
and other borrelial or spirochetal infections can mimic fibromyalgia
and chronic fatigue syndrome symptoms.
Subsequently these patients may not have been correctly advised to
follow up the broad spectrum antibiotic treatment with a suitable
course of probiotics and/ or prebiotics and so they often develop
severe intolerance and allergy of various products.
Some CFS and Fibromyalgia patients may have had severe gut viruses like
Epstein Barr or Coxsackie strains.
Some patients have descended into Chronic Fatigue and Fibromyalgia with
the recognized trigger being an apparent episode of food poisoning or
ingesting some other foreign chemical or toxin.
Often, a long history of Irritable Bowel Syndrome (IBS) or Crohns
Disease can precede the onset of Chronic Fatigue, or the muscular and
joint symptoms associated with a diagnosis of Fibromyalgia.
These digestive and intestinal symptoms often lead to the diagnosis of
The theory behind Leaky Gut is that large immunologically active cells
can pass across the weakened intestinal wall of the patients gut and
enter the bloodstream where they are identified as alien to the host
and so activate a powerful immune response.
As the immune system (which is largely based around the intestines)
fires repeatedly in this way, sufferers develop a variety of allergies
to various foods and substances.
Foods that present particular interest to a Leaky Gut are dairy,
gluten, grain, egg and yeast type foods. A host of airborne toxins are
also implicated in allergies.
By intensive research into the Leaky Gut theory Dr Meirlier identified
that a Leaky Gut reliably produces a by-product gas - Hydrogen
This reaction appears consistently in 80 to 90% of recognized
Fibromyalgia and CFS patients with digestive involvement. This gas is
harmless in small quantities but very toxic in large quantities as
produced by CFS sufferers.
The research revealed the following data related to excessive H2S
production in CFS/ Fibromyalgia sufferers:
H2S is a nasty neuro-toxin, causing light and noise
Other negative reactions can be failure of the core energy producing
cells the mitochondria, immune depression, low lymphocyte levels, gut
bacteria overproduction, a rise in oxidative tissue damage and
retention of heavy metals, particularly mercury, in the body.
Mercury is generally recognized as extremely dangerous. In severe CFS
and Fibromyalgia cases, sufferers can develop rogue prions which can
cause havoc with energy metabolism.
The reason tackling the Leaky Gut is so important is that it could in
some cases be directly at the core of a knock-on flow, a downward
spiral of symptoms further down a long chain that eventually results in
the lymphatic and mitochondrial failure of Chronic Fatigue and
We know already that the sympathetic nervous system is in disarray in
fatigue patients. We also know that these systems are largely situated
around the gut, the intestines, digestive system and bowel.
In the next part of this series i examine the effects of Leaky Gut and
H2S on the Sympathetic nervous system, the direct implications for H2S
on the Hypothalamic Pituitary Axis (HPA) and the associated knock on
effects for the entire endocrine system and immunity.
Finally I discuss how to treat, prevent, and repair the damage caused
by this downward spiral.
Haslam, (B.A, M.Sc, PgDip)
CFS/ Fibromyalgia Research.
CFS/ Fibromyalgia Sufferer.
Fibromyalgia/ Chronic Fatigue
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